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lunes, 9 de junio de 2014
First new river dolphin species found since World War I
Artículo completo: http://www.iflscience.com/plants-and-animals/first-new-river-dolphin-species-found-world-war-i
viernes, 30 de mayo de 2014
miércoles, 21 de mayo de 2014
El ranking de salarios anuales en Estados Unidos, cual es la comparación con su país ???
Fuente: http://www.medscape.com/features/slideshow/compensation/2014/internal-medicine?src=drm_int_ret_comp_0514#2
jueves, 15 de mayo de 2014
miércoles, 7 de mayo de 2014
Alteration in fasting glucose after prolonged treatment with a thiazide diuretic
Alteration in fasting glucose after prolonged treatment with a thiazide diuretic
Diabetes Research and Clinical Practice, 05/02/2014 Clinical Article Clinical Trial Below
Karnes JH, et al. – The results indicate that prolonged thiazide treatment duration is associated with increased FG and that overall glycemic status worsens when thiazide/thiazide–like diuretics are combined with β blockers.
Methods
Results
Methods
- The authors conducted an observational, non–randomized, open label, follow–up study of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) and PEAR–2 studies.
- They enrolled previous participants from the PEAR or PEAR–2 studies with at least 6 months of continuous treatment with either hydrochlorothiazide (HCTZ) or chlorthalidone.
- Linear regression was used to identify associations with changes in FG after prolonged thiazide and thiazide–like diuretic treatment.
Results
- A total of 40 participants were included with a mean 29 (range 8–72) months of thiazide treatment.
- FG increased 6.5 (SD 13.0) mg/dL during short–term thiazide treatment and 3.6 (SD 15.3) mg/dL FG during prolonged thiazide treatment.
- Increased FG at follow–up was associated with longer thiazide treatment duration (β=0.34, p=0.008) and lower baseline FG (β=–0.46, p=0.02).
- β blocker treatment in combination with prolonged thiazide diuretic treatment was also associated with increased FG and increased 2–h glucose obtained from OGTT.
sábado, 3 de mayo de 2014
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