domingo, 4 de marzo de 2012

New Guideline on Diabetic Neuropathic Pain Rx: Is It Really New?

The finding that has drawn most attention is that pregabalin(Drug information on pregabalin) (Lyrica) has the most support for the treatment of DNP based on the extent and quality of published studies. However, the guideline also found that several other medications had a high level of support. These include:
o Antidepressants (ie, amitriptyline(Drug information on amitriptyline) [Elavil], duloxetine(Drug information on duloxetine) [Cymbalta], venlafaxine [Effexor], all serotonin-norepinephrine reuptake inhibitors)
o Anticonvulsants (gabapentin [Neurontin] and sodium valproate(Drug information on valproate)
o Opioids (dextromethorphan, morphine, tramadol [Ultram], and oxycodone(Drug information on oxycodone))
o Capsaicin (Zostrix)
o Isosorbide dinitrate(Drug information on isosorbide dinitrate) spray, a vasodilator.

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