DEFINICION de HTA resistente o refractaria:

Resistant, or refractory, hypertension is defined by a blood pressure of at least 140/90 mm Hg or at least 130/80 mm Hg in patients with diabetes or renal disease (i.e., with a creatinine level of more than 1.5 mg per deciliter [133 μmol per liter] or urinary protein excretion of more than 300 mg over a 24-hour period), despite adherence to treatment with full doses of at least three antihypertensive medications, including a diuretic.

(Patients who have recently received a diagnosis of hypertension or who have not yet received treatment should not be considered to have resistant hypertension, regardless of their blood-pressure level).


Fuente: N Engl J Med 2006; 355:385-392July 27, 2006